Oral Medications

Phosphodiesterase type 5 inhibitors (PDE5 inhibitor) are oral medications used to block degradative action in the smooth muscle cells lining the blood vessels.  These oral drugs increase the release of nitric oxide, that assist in the dilation of arteries, which results in an increased blood flow into the penis. One thing to be noted here is that these drugs don’t cause sexual stimulation directly rather potentiate the sexual excitement and cause erections to become harder than before.  Since they dilate the blood vessels, these drugs are contraindicated in patients with cardiovascular diseases and hypotension. While PDE5 inhibitors are generally well tolerated, the occurrence of side effects is common and depends on the dose and type of agent. Headache is very common, as well as dizziness, flushing and nasal congestion. Back pain and muscle aches are also common in patients taking tadalafil.

“A great place to start for men over 30” says Dr. Wood of Men’s Health Partners. “Ideally, taking a pill that 45 min later causes an erection is the outcome we want for everyone. Unfortunately, it’s not one-size fits-all and we have to take the good with the bad. The bad being side effects that come with all pharmaceuticals.



Ease of Use


A trial of 348 patients found that thrity-six hours after dosing tadalafil 59.2% of intercourse attempts were successful.

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